Diagnostic performances and thresholds: The key to harmonization in serological SARS-CoV-2 assays?
نویسندگان
چکیده
منابع مشابه
A Brief Review on the Advancement of the Molecular and Serological Diagnosis of SARS-CoV-2
The novel coronavirus, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has introduced as causative agent for coronavirus disease 2019 (COVID-19) since the 2019 December. Human coronaviruses are classified in Nidovirales order and Coronavirdiae family. This family includes four genera. The SARS-CoV-2 is a member of Betacoronavirus genera and Sarbecovirus linage (linage B). There is ...
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Abstract Background and Objectives Clinical features of SARS-COV-2 virus include fever, headache, cough, sore throat, and shortness of breath, and in severe forms it leads to disseminated intravascular coagulation, septic shock, and ultimately death. Excessive secretion of proinflammatory cytokines such as TNF-α, IL-6, and IL-1 leads to cytokine storms in this disease. The emergence of new va...
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Undoubtedly, vaccination can be one of the promising approaches to control infectious diseases such as the COVID-19 pandemic. Inactivated viral vaccines have a history of "vaccine-induced enhanced disease", which may occur when neutralizing antibodies bind to viral antigens without blocking or clearing the infection. This can cause additional inflammation through the mechanisms described for ot...
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ژورنال
عنوان ژورنال: Clinica Chimica Acta
سال: 2020
ISSN: 0009-8981
DOI: 10.1016/j.cca.2020.05.050